Author: trsrinivas

We thank Earlier.org for funding our research on profiling subnucleosomes in plasma.

Excited to welcome Grace and Kamesh to the lab! Read more about them in the member page.

Our paper describing a new histone H3 mutant used in chemical cleavage mapping is out in Genome Biology! This mutation along with phenanthroline makes histone H3 a site-specific nuclease, releasing exactly 51 bp from a single nucleosome. Center of the 51 bp fragment is the exact nucleosome position (no processing – WYSIWYG bp resolution).

Ramachandran Lab is officially open!

Our paper on identifying sub-nucleosome structures in cells made the cover in Molecular Cell.